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Amoxapine (Asendin®; Asendis®; Defanyl®; Demolox®; Moxadil®) is a tricyclic antidepressant of the dibenzoxazepine class. It is used in the treatment of depression, panic disorders and bipolar disorder.
Amoxapine is a strong reuptake inhibitor of norepinephrine and weak reuptake reuptake inhibitor of serotonin. One of its major metabolite, 7-hydroxyamoxapine, has a dopamine receptor blocking effect.
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