Citrulline Citrulline

Citrulline - Definition and Overview

The chemical compound citrulline is an amino acid whose structure is:

H2N-CONH-CH2-CH2-CH2-CHNH2-COOH

L-citrulline is made from L-ornithine and carbamoyl phosphate in one of the central reactions in the urea cycle. It is also produced from L-arginine as a by-product of the reaction catalyzed by the enzyme NO synthase. L-citrulline, while being an amino acid, is not involved in protein synthesis and is not one of the amino acids coded for by DNA.

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