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The Combahee River is a short blackwater river (length needed) in the Southern Lowcountry region of South Carolina formed at the confluence of the Salkehatchie and Little Salkehatchie rivers near the Islandton community of Colleton County. Part of its lower drainage basin combines with the Ashepoo and Edisto's to form the ACE Basin National Wildlife Refuge. The Combahee empties into St. Helena Sound near Beaufort, which in turn empties into the Atlantic Ocean.
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