David Bremner Henderson (March 14, 1840–February 25, 1906) was a prominent U.S. politician of the 1890s and 1900s. He served as Speaker of the United States House of Representatives from 1899 to 1903, and served as a Republican from Iowa in the House from 1883 to 1903. This article incorporates facts obtained from the public domain Biographical Directory of the United States Congress.