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Diazinon (O,O-diethyl 0-2-isopropyl-6-methyl(pyrimidine-4-yl) phosphorothioate), a colorless to dark brown liquid, is a nonsystemic organophosphate insecticide used to control cockroaches, silverfish, ants, and fleas in residential, non-food buildings. Bait is used to control scavenger wasps in the western U.S. Diazinon is a thiophosphoric acid developed in 1952 by Ciba-Geigy, a Swiss chemical company (later Novartis and then Syngenta).
Diazinon kills insects by inhibiting acetylcholinesterase, an enzyme needed for proper nervous system function. Diazinon has a low persistence in soil. The half-life is 2 to 4 weeks. The symptoms associated with diazinon poisoning in humans include weakness, headaches, tightness in the chest, blurred vision, nonreactive pinpoint pupils, salivation, sweating, nausea, vomiting, diarrhea, abdominal cramps, and slurred speech.
In 1988, the Environmental Protection Agency prohibited the use of Diazinon on golf courses and sod farms because of decimation of bird flocks that congregated in these areas. In the United States as of December 31, 2004, it became unlawful to sell diazinon outdoor, non-agricultural products. It is still legal for consumers to use diazinon products, provided that they follow all label directions and precautions
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