Esophagitis (aka reflux esophagitis) is inflammation of the esophagus. It may be caused by gastroesophageal reflux disease (GERD), infections, chemical injury, physical injury, or it may be idiopathic. The most common cause is gastroesophageal reflux disease. Other causes of esophagitis include infections (most commonly candida, herpes simplex and cytomegalovirus. These infections are typically seen in immunocompromised people, such as those with AIDS. Chemical injury by alkaline or acid solutions may also cause esophagitis, and is usually seen in children or in adults who attempt suicide. Physical injury resulting from radiation therapy or by nasogastric tubes may also be responsible.
