Frank Schlesinger (May 11 1871 – July 10 1943) was an American astronomer.

He won the Gold Medal of the Royal Astronomical Society in 1927 and the Bruce Medal in 1929.

He worked at Yerkes Observatory and pioneered the use of photographic methods to determine stellar parallaxes. He was director of Allegheny Observatory from 1905 to 1920 and Yale University Observatory from 1920 to 1941.

He made major contributions to astrometry. He compiled and published the Yale Bright Star Catalogue.