Glafkos Ioannu Klerides (born 1919) is a Greek-Cypriot politician and former president of the Republic of Cyprus.

During World War II, he served in the British Royal Air Force and was shot down over Germany, spending years as a prisoner of war.

After Cyprus became independent in 1960, Klerides gained political power as a member of the United Democratic Party. On July 23, 1974, amidst the turmoil following an invasion by Turkey and a military coup several days earlier, Klerides became acting President until it was safe for the previous President, Archbishop Makarios III to return to Cyprus and serve as President again later in 1974.

Later, as a member of the conservative Democratic Rally (Demokratikos Synagermos), he served as President for 10 years between 1993 and 2003. He was elected to two five-year terms, in 1993 and in 1998. In 1998 his main opponent was Georgios Iakovou. He was defeated in the Presidential elections of 2003 by Tassos Papadopoulos.