a position on the DNA where mutations occur with an unusual high frequency
a position on the DNA where recombination occurs with an unusual high frequency
In meteorology, a hotspot is an area where the atmosphere is relatively hot. Examples of hotspots include the air over a desert or the region of Jupiter where the Galileo probe's atmospheric sub-probe descended.
A hotspot is a Wi-Fi access point or area, in particular for connecting to Internet.
PDA Hotspots (http://www.wacklepedia.com/pdahotspots/pda_hotspots.htm) - List of websites that adjust to the small PDA screen
HauteSpot Networks Solution Documents (http://www.hautespot.net/solutions/index.html) - Set of example documents showing how hotspots can be set up for various organizations such as schools, government, restaurants, cafes, hotels, etc