The Hoxnian interglacial is a name for an interglacial period which occurred between 300,000 and 200,000 years ago. The name is used by British geologists and archaeologists who named it after the Hoxne in the English county of Suffolk where some of the deposits it created were first found.

It is a Pleistocene stage of the Quaternary period and is analogous to the Yarmouth interglacial in North America, the Holstein interglacial in northern Europe and the Mindel-Riss interglacial in the Alps. It was a warm period and its deposits directly overlie material from the preceding Anglian glaciation and lie beneath those from the following Wolstonian glaciation

There is some evidence that Hoxnian material represents more than one glaciation. Clactonian and Acheulean flint tools and human remains have been found dating to this stage.