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Hua Tuo (华陀; d. 208 AD) is a famous Chinese physician during the Three Kingdoms era. He was the first person to perform surgery with the aid of anesthesia, some 1600 years before Europeans did. He was jailed and ordered to death by Cao Cao because he proposed opening of Cao Cao's skull to cure a brain tumor. Cao Cao thought Hua Tuo has the intention of killing him by opening his skull. Upon the death of Hua Tuo, he gave his medicine booklet to a prison officer, however, the wife of the prison officier burned the booklet and only two pages of Hua Tuo's works were left. Hua Tuo is often being praised as the "miracle working doctor" (神醫) in China.
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