Mesalamine Mesalamine

Mesalamine - Definition and Overview

Mesalamine, also known as 5-aminosalicylic acid (5-ASA), is an anti-inflammatory drug used to treat inflammation of the rectum, mild to moderate ulcerative colitis and inflammation of the lower colon. Chemically, it is 5-amino-2-hydroxybenzoic acid. The empirical formula is C 7 H 7 NO 3 and its molecular weight is 153.14.

It is sold in the U.S. under the names:

  • CANASA: Rectal suppository with 500 mfg of mesalamine in a base of Hard Fat NF.
  • ROWASA: Rectal suppository & suspension enema.
  • PENTASA: Suspension enema.
  • ASACOL: Suspension enema & 400mg tablets

Known side effects

  • Cramping
  • Sudden severe stomach pain
  • Bloody diarrhea
  • Fever
  • Severe headache
  • Rash
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