Metoprolol Metoprolol

Metoprolol - Definition and Overview

Metoprolol is a beta blocker drug used in treatment of several diseases of the cardiovascular system. It is marketed under the brand name Lopressor by Novartis, and Toprol (in the USA) and Seleken (elsewhere) by AstraZeneca.

Properties:

  • cardioselective
  • lipophilic
  • without intrinsic sympathomimetic activity (ISA)
  • without membrane stabilizing activity
  • short half-life must be taken at least twice daily or SR preparations

Indications:

In the United States and most other countries, this medication is available only by prescription.

References

  1. Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF) (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10376614&dopt=Abstract) Lancet. 1999 Jun 12;353(9169):2001-7

Example Usage of Metoprolol
MDLinx: Cardio: Comparison of Ivabradine Versus Metoprolol in Early Phases of Reperfused Anterior Myocardial Infarction With Imp http://url4.eu/tBZb
JaniceChase: What Does Metoprolol Look Like - HealthCentral http://bit.ly/NKpV
JMLIBRA: she got percocet, oxycodon, lorazepam (I OD'd on this a couple months ago), Metoprolol, some generic percocet, what should i take?
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