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In computing, the most significant bit (MSB) is the bit position in a binary number having the greatest value. The MSB is sometimes referred to as the left-most bit.
In referencing specific bits within a binary number, each bit is assigned a bit number, ranging from zero to n (depending on the number of bits in the number.) Bit zero may refer to the LSB or the MSB, depending on the endianness.
By extension, the most significant bits (plural) are the bits of the number closest to, and including, the MSB.
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