Opportunity Knocks was a UK television talent show originally hosted by Hughie Greene.

It was shown on ITV from the 1950s until 1978 and later revived briefly on BBC. Entertainers who appeared included: Mary Hopkin, Bonnie Langford, Les Dawson, Little and Large, Bobby Crush, Peters and Lee, Lena Zavaroni, Frank Carson, Max Boyce, Pam Ayres and Freddie Starr.