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A paraprotein is an abnormal protein in the urine or blood, most often associated with multiple myeloma.
These are immunoglobulins or immunoglobulin light-chains that are produced by the clonal proliferation of plasma cells. Paraproteins form a narrow band, or 'spike' in protein electrophoresis as they are all the exact same protein.
Light-chains in the urine are called Bence Jones proteins.
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