Pioglitazone - Definition

In medicine and pharmacology, pioglitazone is a member of the drug class of the thiazolidinediones.

It is being marketed as Actos® by the pharmaceutical companies Takeda and Eli Lilly.

Like other thiazolidinediones, its mechanism of action is by activation the intracellular receptor class of the peroxisome proliferator-activated receptors (PPARs), specifically PPARγ.

Side-effects and contraindications

See main article: thiazolidinedione

See also

• Anti-diabetic drugs
• Peroxisome proliferator-activated receptor

External links

• MedlinePlus article (http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a699016.html) on pioglitazone.
• Diabetes monitor (http://www.diabetesmonitor.com/actos.htm) on Pioglitazone
• Actos / Pioglitazone Fact Sheet (http://www.fact-sheets.com/health/drugs-medications/actos/)