Regulatory_T_cell Regulatory_T_cell

Regulatory T cell - Definition

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Regulatory T cells (also known as suppressor T cells) are characterised by virtue of their expression of the cell surface markers CD4 and CD25. They help to suppress or prevent autoimmunity by counteracting self-reactive lymphocytes. Some (but not all) do so by secreting inhibitory cytokines that block the activation of macrophages or other lymphocytes. It is unclear what factors cause immature T cells to develop into regulatory T cells, but they may do so in thymus or in peripheral tissues

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