|
Sigma factor (σ factor) is an initiation factor that binds to RNA polymerase and promotes attachment to promoter sites on DNA.
Structure
Sigma factor has four main regions:
N----------C
1 2 3 4
- Region 1 regulates interaction with DNA.
- Region 2 binds RNAP and binds to the -10 promoter site.
- Region 4 binds to the -35 promoter site.
|
