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This is the name given to the northwest region of the state of South Carolina, United States of America. Counties in this region include Cherokee, Spartanburg, Greenville, Pickens, Oconee, and Anderson. Greenville, the third largest city in South Carolina, is located in this region. The upstate is the fastest growing region in the state, with several commercial and industrial areas, including the BMW Manufacturing Plant in Greer.
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