The South Shore can refer to:

• South Shore, Long Island, southern edge of Long Island, NY, area which encompasses the Great South Bay
• South Shore (Nova Scotia), an area of Nova Scotia
• South Shore (electoral district), the riding that covers that part of Nova Scotia
• South Shore in Kentucky
• South Shore (Massachusetts), a part of Massachusetts
• South Shore in South Dakota
• South Shore, Staten Island, a series of neighborhoods in Staten Island, New York