Succinyl-Coenzyme A, generally abbreviated as Succinyl-CoA is a combination of succinic acid and coenzyme A.
Source
It is an important intermediate in the citric acid cycle, where is it synthetised from α-Ketoglutarate by α-ketoglutarate dehydrogenase through decarboxylation. During the process, coenzyme A is added.
Fate
It is converted into succinate through the hydrolytic release of coenzyme A by succinyl-CoA synthetase.
Another fate of succinyl-CoA is porphyrin synthesis, where succinyl-CoA and glycine are combined by ALA synthase to form δ-aminolevulinic acid (dALA).
|
