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Trypsinogen (EC 3.4.23.18/20/21/23/24/26) is the precursor form of the pancreatic enzyme trypsin. It is activated by enterokinase, which is found in the intestinal mucosa, to form trypsin. Once activated, the tyrpsin can activate more trypsinogen into trypsin.
Serum trypsinogen is measured using a blood test. High levels are seen in acute pancreatitis, and cystic fibrosis.
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