Three ships of the United States Navy have been named USS San Diego, after the city of San Diego, California.

• The first San Diego was originally the armored cruiser California (ACR-6).

• The second San Diego (CL-53) was a light cruiser commissioned in 1942 in service throughout the Pacific War, and decomissioned 1946.

• The third San Diego (AFS-6) was a combat store ship in service from 1969 to 1997.

• The sixth ship of the new San Antonio class LPD will be named in honor of San Diego.