West Ruislip is the western terminus of the Central Line, and a stop on the Chiltern Railways service from Marylebone towards High Wycombe and Birmingham Snow Hill. Its original name was "West Ruislip (for Ickenham)", but was truncated in the 1980s.

The Central Line platforms are arranged in an island layout, with the lines extending past the platforms and under the road bridge to buffer stops a short distance westwards. This is a legacy of the original design proposals, which as part of the 1935-40 New Works plan saw Central Line services extending from North Acton junction to Denham. However, the post-war passing of the Town and Country Planning acts blocked the continuation of the pre-war speculative housing development which the extension to Denham would have served, and the extension was cut back to West Ruislip. Its legacy can still be seen in the very wide formation west of the road overbridge, where the width of the fenced land between the existing running lines and the gardens of the adjacent houses to the south of the line indicate where the extension would have run.

The depot to the east of the station, south of the running lines, handles many empty stock movements into and out of the station as trains come into and out of service.

Two more platforms for the Chiltern services are located north of the Central Line platforms. The original layout had two through roads and two platform roads, but simplification of the layout when the old manual signal box closed removed the westbound platform road and widened the westbound platform. Only the eastbound services into Marylebone now have a through and a platform road. The eastbound platform road rejoins the through road a few hundred yards east of the platform end. This platform road, which formerly extended back as far as Northolt Junction adjacent to South Ruislip station, was closed and lifted some years ago. Chiltern Railways have indicated that four roads may be restored at some time in the future.

A shunting neck is located on the south side of the line west of the road overbridge, to allow stock and freight (mainly ballast train) movements into and out of West Ruislip LUL depot. On the north side of the line are two sidings, at present used only for the occasional ballast or works train. For a period some years ago, a shuttle service to Marylebone used these sidings as a reversing point; this service has ceased, and all trains now run through.

Preceding station	Underground Lines			Following station
Terminus		Central Line		Ruislip Gardens