Methotrexate - Dictionary Definition and Overview

Methotrexate :  (noun)

1: toxic antimetabolite that limits cellular reproduction by acting as an antagonist to folic acid; used to treat certain cancers and psoriasis and rheumatoid arthritis [syn: methotrexate sodium, amethopterin]

Based on WordNet 2.0

Methotrexate :  protein .

Methotrexate (MTX) is used to treat diseases associated with abnormally rapid cell growth such as certain tumors and osteosarcoma .

Aside from psoriasis, methotrexate has also been found helpful in treating rheumatoid arthritis .

Methotrexate, especially in higher doses, can cause adverse reactions. The most frequent reactions include mouth sores, stomach upset, and low white blood counts. Methotrexate can be toxic to the bone marrow and liver.

Based on WordNet (r) 2.0 (August 2003)
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