P53 - Dictionary Definition and Overview

P53 :  p53: A tumor suppressor. The designation "p53" stands for "protein 53 kilodaltons" in size.

p53 is a specific genes , p53 normally controls cell growth. If p53 is physically lost or is not functioning (because it has been inactivated), this may permit the cell to divide without restraint.

The level of p53 has prognostic (predictive) value. For example, sign that p53 is not working properly to suppress the growth of the tumor.



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