Ligase (626 bytes)
1: ...C 6''' in the [[EC number]] classification. Many ligases are also known as "synthases" or "synthetases" b...
3: ..., one of the most frequently used ligase is [[DNA ligase]]. It is used to connect [[DNA]] fragments toget...
7: [[Category:Ligases]]

DNA ligase (834 bytes)
1: ...[[enzyme]] that repairs broken DNA strands. DNA [[ligase]] (EC 6.5.1.1) is a particular type of enzyme th...
3: An example of how a ligase works (with [[sticky end]]s):
13: ...tp://nist.rcsb.org/pdb/molecules/pdb55_1.html DNA Ligase: PDB molecule of the month]
17: [[Category:Ligases]]

Ubiquitin ligase (1149 bytes)
1: ...ine]] residue on a target protein. The ubiquitin ligase is typically involved in polyubiquitylation: a se...
3: ...e is one major E1 enzyme, shared by all ubiquitin ligases, which uses [[adenosine triphosphate|ATP]] to ac...

Trans-splicing (207 bytes)
1: ...ryote]]s where exons from two RNA molecules are [[Ligase|ligated]] in an intermolecular reaction.

Parkin (658 bytes)
1: '''Parkin''' is an [[E3 ligase]] in the [[ubiquitin-proteasome system]]. Many [...

Okazaki fragment (577 bytes)
1: ...between the fragments is linked together by [[DNA ligase]].

DNA polymerase I (838 bytes)
3: ... [[nucleotides]] (see ''[[DNA replication]]''). [[Ligase]] then joins the various fragments together into ...

Anaphase-promoting complex (1083 bytes)
1: ... initiate [[anaphase]]. The APC is a [[ubiquitin ligase]] that marks target proteins for degradation by t...

Sticky end/blunt end (1649 bytes)
19: ... fragments may then be covalently bonded by [[DNA ligase]]. Blunt ends may be ligated, but the reaction i...

Lagging strand (1246 bytes)
7: ...e slightly different kinds of nucleotides). [[DNA ligase]] joins the fragments together.

Site-directed mutagenesis (1478 bytes)
3: ...r]] by means of [[restriction enzyme]]s and [[DNA ligase]]. The expression vector is then typically insert...

Topoisomerase (2440 bytes)
8: ...x, twisting it around the other strand, and [[DNA ligase|religating]] (reconnecting) the nicked strand. (...

EC number (2494 bytes)
12: * EC 6 ''[[Ligase]]s'': join two molecules with [[covalent bond]]s

Phosphodiester bonds (2463 bytes)
19: ...the backbone left by [[DNA polymerase I]]. [[DNA ligase]] is able to form a phosphodiester bond between t...

DNA replication (6428 bytes)
1: ...led [[Okazaki fragment]]s). Another enzyme, [[DNA ligase]] (yellow), then stitches these together into the...
18: ...lled [[Okazaki fragment]]s. Another enzyme, [[DNA ligase]], is used to connect the fragments.

Ubiquitin (3185 bytes)
18: ...elman syndrome]], ''UBE3A'', encodes an ubiquitin ligase (E3) enzyme termed E6-AP.

Selenocysteine (3249 bytes)
6: ...s are initially charged with serine by seryl-tRNA ligase, but the resulting Ser-tRNA(Sec) is not used for ...

Nuclease (6335 bytes)
29: ...o each other--they are "sticky" for each other. [[Ligase]] enzyme is then used to join the phosphate backb...

Restriction enzyme (6623 bytes)
1: ...e reformed by other enzymes known as [[DNA ligase|ligases]], so that '''restriction fragments''' carved fr...

List of molecular biology topics (10731 bytes)
20: ...otide]] - [[diploid]] - [[direct repeat]] - [[DNA ligase]] - [[DNA polymerase]] - [[DNA replication]] - [[...
41: ...leucine zipper]] - [[leukemia]] - [[library]] - [[ligase]] - [[linear epitope]] - [[linkage]] - [[linker]]...

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